ADRB1 anticorps (Internal Region)

N° du produit ABIN7540608

N° du produit (Fournisseur): 600-401-mh1s

L’anticorps Lapin Polyclonal anti-ADRB1 a été validé pour WB, ELISA et FACS. Il convient pour détecter ADRB1 dans des échantillons de Humain.

Aperçu rapide pour ADRB1 anticorps (Internal Region) (ABIN7540608)

Antigène: ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADRB1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-ADRB1 anticorps

Épitope: Internal Region

N° du produit (Fournisseur): 600-401-mh1s

Fournisseur: Rockland

Fonction: BETA 1 ADRENERGIC RECEPTOR Antibody

Réactivité croisée (Details): This affinity purified antibody is directed against human beta 1 adrenergic.

Purification: The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.

Stérilité: Sterile filtered

Immunogène: Anti-Beta 1 Adrenergic Receptor (RABBIT) Antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal portion of human beta 1 adrenergic conjugated to Keyhole Limpet Hemocyanin (KLH).

Isotype: IgG

Information d'application

Indications d'application:

ELISA_Dilution: 1:10,000-1:15,000

Flow_Cytometry_Dilution: 1:20

Western_Blot_Dilution: 1:1000

Commentaires:

Suggested Applications: User Optimized
Anti-Beta 1 Adrenergic Receptor Antibody has been tested in ELISA, WB, and FLOW. Expect a band at ~51kDa in western blot using appropriate lysates. Positive control used: human heart muscle membrane tissues in WB and NCCIT cells in FLOW. Although not tested, this antibody may be suitable in IHC.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.

Date de péremption: 12 months

Détails sur ADRB1

Antigène: ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))

Autre désignation: ADRB1

Sujet: Rabbit Anti-Beta-1 Adrenergic receptor Antibody, Rabbit Anti-Adrenergic ß1R Antibody, Adrenoceptor Beta 1, Adrenergic Beta-1-Receptor, Beta-1 Adrenoreceptor, Beta-1 Adrenoceptor, Adrb1r, B1AR, Beta-1 Adrenergic Receptor, BETA1AR, RHR, Beta-1 adrenergic receptor,The adrenergic beta1 receptor (beta1-adrenoceptor) is a member of the adrenergic receptor group of G-protein-coupled receptors that also includes alpha1A, alpha1B, alpha1D, alpha2A, alpha2B, alpha2C, beta2 and beta3. They are located primarily in the CNS, heart, coronary artery, kidney and muscle. Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. Anti-Beta 1 Adrenergic Receptor Antibody is useful for researchers interested in cardiac function and G-protein signaling pathways.

ID gène: 153

NCBI Accession: NP_000675

UniProt: P08588

Pathways: cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Brown Fat Cell Differentiation